Postdoc Practice Job Talk

Please see the information below regarding an upcoming practice job talk. Attendance and feedback at the talk would be greatly appreciated. We hope to see you there.

WHAT: Postdoc Practice Job Talk: Tatyana Sysoeva, in the group of Lingchong You, Department of Biomedical Engineering

WHEN: Tues Jan 31, 9-10 am (Tomorrow)
WHERE: Rm 103 Bryan Research Bldg

The Duke University Postdoc Association (DUPA) and the Office of Postdoctoral Services provide postdocs the opportunity to practice their job talks and get valuable feedback from a diverse and intelligent audience – this means YOU!

On Jan 31 at 9 am in room 103 Bryan Research Bldg, Tatyana Sysoevafrom the group of Lingchong You, Department of Biomedical Engineering, will present her talk on “Bacterial trade: export and import of macromolecular goods” (abstract below). We encourage postdocs to attend and support Tatyana by providing feedback! You don’t have to be in the same field of study; presenters receive valuable info from audience members about clarity, communication style, and other ‘big picture’ issues.

Abstract: Bacterial trade: export and import of macromolecular goods


Bacteria developed numerous ways to adapt to changes in their environment. Transport of macromolecules across bacterial cell envelop is one of the ways bacteria survive and thrive by gaining access to nutrients, releasing by-products, exchanging genes, or secreting toxins. I will present two studies focused on analyses of the mechanism of protein export and DNA import in a model bacterium Bacillus subtilis. Using a combination of functional, biochemical, and structural methods, I established molecular details of the novel secretory pathway of ESX protein secretion and zinc-involvement in the development of natural competence state in this model microorganism. These new details, revealed by working with B. subtilis, shed light on the mechanism of virulence factor secretion in human pathogens Staphylococcus aureus and Mycobacterium tuberculosis as well as open a new avenue in studies of spreading of antibiotic resistance genes.

Questions? Email Xiaojun Li (Grace), DUPA Professional Development Chair, at

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